Research Rookies explore fungal growth and dissemination

By Lauren Dielman

A certain kind of fungal growth, Aspergillus nidulans, may affect patients with weak immune systems.

Research Rookie Justin Durancik, sophomore biology major, and Ana Calvo, professor of biological sciences, will conduct an investigation of fungal growth and dissemination. Durancik said the main focus of his research will be Aspergillus nidulans.

“This fungus serves as a model organism for similar fungi that are common plant pathogens and opportunistic human pathogens affecting patients with weak immune systems,” Durancik said.

Calvo said the main goal of their project is to maximize the advantages of the fungal compound.

“The project includes the designing of strategies to increase the synthesis of beneficial fungal compounds such as antibiotics and decrease those that are detrimental such as carcinogenic toxins,” Calvo said.

Durancik said his research will ultimately contribute to VeA, a global regulator that controls fungal morphogenesis, pathogenicity and the combination of toxins and antibiotics. Fungal morphogenesis occurs when the fungus develops and grows and pathogenicity occurs when there is an infection from a virus or bacteria.

Calvo said the main role of the mentor is to oversee the Research Rookie’s work.

“Also, the mentor is responsible for training the student in all of the techniques required to achieve project objectives,” Calvo said.

The mentor also supervises the Research Rookie as he or she writes a research proposal interpreting the results and presenting their work.

Durancik said he enjoys learning the hands on technique in the field of biology and he has created many relationships with faculty members and students involved in the Research Rookies program.